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KMID : 0363219940320010177
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Korean Journal of Dermatology
1994 Volume.32 No. 1 p.177 ~ p.181
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A Case of Cutaneous Epithelioid Angiosarcoma
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Abstract
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The epithelioid angiosarcoma is recently described as a variant of angiosarcoma based on its pathological feature, which is characterized the epithelioid or histiocytoid morphology of the malignant tumor cells. The existence of vascular
endothelial
tumor with an epithelioid feature has been accepted for many years, most notably in the forms of epithelioid hemangioma and epithelioid hemangioendothelioma. In recent years, cutaneous angiosarcoma with epitheliod morphology have been reported as
a
epithelioid angiosarcoma in the literatures.
A 60-year-old man presented with a mild tender erythematous 2×2×2.5cm sized soft fluctuating signle nodule with dark hemorrhagic crust on the left forehead for 3 months. He had had an abrasion wound on the lesion site of the forehead by an
accidental
trauma 3 months before the lesion appeared.
Histopathological findings revealed that the tumor mass was chiefly composed of solid sheets of poorly differentiated malignant cells with an epithelioid feature. The characteristics of classical angiosarcoma such as primitive vascular spaces and
clefts
with malignant cells, and proliferating vessels were also found in some areas. The immunohistochemical stain with the factor VIII related antigen was focally reactive in the tumor cells.
Unfortunately he refused further treatment and expired 7 months after discharge at home without knowing the direct cause of his death.
We report herein an interesting and rare case of the cutaneous epithelioid angiosarcoma which had typical clinical and histopathological findings and suggested as a case with a very aggressive course. (Kor J Dermatol 1994 ; 32 (1) : 177~181)
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